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leprae. Anin silicostudy was executed to know the molecular interactions among DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 had been revealed to own better inhibitory exercise againstM. lepraeDNA gyrase than Many others. On top of that, Evaluation using quinolone-resistantM. lepraeDNA gyrases confirmed that WQ-3334 had larger inhibitory activit